What does a Cytogenetic Technologist do?

Analyze chromosomes found in biological specimens such as amniotic fluids, bone marrow, and blood to aid in the study, diagnosis, or treatment of genetic diseases.

Jobs Roles

  • Develop and implement training programs for trainees, medical students, resident physicians or post-doctoral fellows.
  • Stain slides to make chromosomes visible for microscopy.
  • Summarize test results and report to appropriate authorities.
  • Select or prepare specimens and media for cell cultures using aseptic techniques, knowledge of medium components, or cell nutritional requirements.
  • Select banding methods to permit identification of chromosome pairs.
  • Identify appropriate methods of specimen collection, preservation, or transport.
  • Prepare slides of cell cultures following standard procedures.
  • Select appropriate methods of preparation and storage of media to maintain potential of hydrogen (pH), sterility, or ability to support growth.
  • Harvest cell cultures using substances such as mitotic arrestants, cell releasing agents, and cell fixatives.
  • Create chromosome images using computer imaging systems.
  • Determine optimal time sequences and methods for manual or robotic cell harvests.
  • Examine chromosomes found in biological specimens to detect abnormalities.
  • Recognize and report abnormalities in the color, size, shape, composition, or pattern of cells.
  • Communicate test results or technical information to patients, physicians, family members, or researchers.
  • Prepare biological specimens such as amniotic fluids, bone marrow, tumors, chorionic villi, and blood, for chromosome examinations.
  • Count numbers of chromosomes and identify the structural abnormalities by viewing culture slides through microscopes, light microscopes, or photomicroscopes.
  • Arrange and attach chromosomes in numbered pairs on karyotype charts, using standard genetics laboratory practices and nomenclature, to identify normal or abnormal chromosomes.
  • Analyze chromosomes found in biological specimens to aid diagnoses and treatments for genetic diseases such as congenital birth defects, fertility problems, and hematological disorders.
  • Input details of specimens into logs or computer systems.
  • Maintain laboratory equipment such as photomicroscopes, inverted microscopes, and standard darkroom equipment.
  • Supervise subordinate laboratory staff.
  • Select appropriate culturing system or procedure based on specimen type and reason for referral.
  • Describe chromosome, FISH and aCGH analysis results in Internations System of Cytogenetic Nomenclature (ISCN) language.
  • Extract, measure, dilute as appropriate, label, and prepare DNA for array analysis.
  • Input details of specimen processing, analysis, and technical issues into logs or laboratory information systems (LIS).
  • Apply prepared specimen and control to appropriate grid, run instrumentation, and produce analyzable results.
  • Develop, implement, and monitor quality control and quality assurance programs to ensure accurate and precise test performance and reports.
  • Evaluate appropriateness of received specimens for requested tests.
  • Communicate to responsible parties unacceptable specimens and suggest remediation for future submissions.
  • Archive case documentation and study materials as required by regulations and laws.
Field Technologist at Zeminwe Recruitment in Paarl 19 hours ago
Foods Product Technologist - Flavors at Gumtree.co.za in Pretoria 19 hours ago
Food Product Technologist at Gumtree.co.za in Pretoria 19 hours ago
Architectural technologist needed urgently! at Gumtree.co.za in Woodstock 19 hours ago
Civil Design Technologist in South Africa 19 hours ago
Civil Design Technologist at Communicate Recruitment: Engineering in South Africa 19 hours ago
Architectural Technologist in South Africa 19 hours ago
Relief Blood Bank Qualified Technician/Technologist at South African National Blood Service in Durban 19 hours ago
Professional Mechanical Design Technologist (Pumping & Pipelines) at Construct Executive Search in Johannesburg 19 hours ago
: Zuid Afrikaans Laboratory: Qualified Clinical Pathology Technologist at Vermaak and Partners Pathologists in Pretoria 1 day ago